Sunday, June 3, 2012

Sorry for the long hiatus....

....I'm officially back after successfully completing my first year of college! Expect more new entries to come up during the summer! AS usual, if you have any suggestions, feel free to email me!

Monday, January 23, 2012

Guestpost: W3Clinic is your online health and medication information center

Some of us cannot afford a doctor's high fees they charge these days. And the environment not getting any better, the frequency with which we get sick is more than before. So in these dire times, how can we remain healthy without spending much of our hard earned money and still be getting the same quality of treatment. Something that can give all this, at one place, without any loopholes, it will certainly be a blessing for anyone and everyone.

W3Clinic is one such website that is a collection of all medicines and drugs, and health conditions. It contains a list of all the drugs present in the market and how to use them along with the side effects it can cause. Moreover, it gives complete information of a particular health condition or disease telling about all the precautions one can take to prevent it and what to do in case one finds oneself suffering from it. It gives home remedies as well as medicinal articles by professionals.

W3Clinic has created an organization that we believe fulfills the promise of health information on the Internet. We provide credible information, supportive communities, and in-depth reference material about health subjects that matter to you. We are a source for original and timely health information as well as material from well known content providers.
He continued, We pride ourselves in knowing our audience's needs and delivering the most appropriate experience. We know that there is a difference between using a health site for health performance" issues (e.g., flat abs) vs. health research needs (e.g., "What is type 2 diabetes?") vs. community support (e.g., "Does anyone else feel like me?") vs. e-commerce. Our mission is to fulfill all these needs in the most appropriate ways possible. We are committed to improving our site. We will continue to publish even more content, communities, and services to help make your life better, to help you find your way when faced with healthcare decisions, and to help you feel better about the health of you and your family.

W3Clinic is an upcoming website and might not be as famous as some other existing ones that are similar, but if they keep working with the same dedication and introduce some innovative ideas, it might become a great website.


Monday, January 16, 2012

Health Website

Recently, I received an email from someone that frequents my site about an informative health website he found. I reviewed the site, and it does have a lot of really good information, ranging from diseases/conditions to medications/treatments. I'll post the body of the email so you all will know more about it. I will also add it to my links page, so check it out sometime!

"W3Clinic is an online, healthcare information center produced by a team of Web professionals and medical experts. It provides easy-to-read, in-depth, authoritative medical information for consumers via its user-friendly and interactive website. 

W3clinic provides the most detailed and credible information on a wide range of health topics, drugs and medications and medical conditions so as to help you feel better about the health of you and your family.

You can read more about it at"

Chromosome II

What is chromosome II?
Chromosome 2 is the second largest human chromosome, spanning more than 243 million building blocks of DNA (base pairs) and representing almost 8 percent of the total DNA in cells. Chromosome II likeley contains between 1,300 and 1,400 genes.

How are changes in chromosome II related to health problems?
Changes in chromosome 2 have been identified in several types of cancer. These genetic changes are somatic, which means they are acquired during a person's lifetime and are present only in certain cells. For example, a rearrangement (translocation) of genetic material between chromosomes 2 and 3 has been associated with cancers of a certain type of blood cell originating in the bone marrow (myeloid malignancies).
Trisomy 2, in which cells have three copies of chromosome 2 instead of the usual two copies, has been found in myelodysplastic syndrome. This disease affects the blood and bone marrow. People with myelodysplastic syndrome have a low number of red blood cells (anemia) and an increased risk of developing a form of blood cancer known as acute myeloid leukemia.
2q37 deletion syndrome
2q37 deletion syndrome is caused by a deletion of genetic material from a specific region in the long (q) arm of chromosome 2. The deletion occurs near the end of the chromosome at a location designated 2q37. The size of the deletion varies among affected individuals. The signs and symptoms of this disorder, which may include intellectual disability, autism, short stature, obesity, and characteristic facial features, are probably related to the loss of multiple genes in this region.
other chromosomal conditions
Another chromosome 2 abnormality is known as a ring chromosome 2. A ring chromosome is formed when breaks occur at both ends of the chromosome and the broken ends join together to form a circular structure. Individuals with this chromosome abnormality often have developmental delay, small head size (microcephaly), slow growth before and after birth, heart defects, and distinctive facial features. The severity of symptoms typically depends on how many and which types of cells contain the ring chromosome 2.
Other changes involving the number or structure of chromosome 2 include an extra piece of the chromosome in each cell (partial trisomy 2) or a missing segment of the chromosome in each cell (partial monosomy 2). These changes can have a variety of effects on health and development, including intellectual disability, slow growth, characteristic facial features, weak muscle tone (hypotonia), and abnormalities of the fingers and toes.
Ideogram of chromosome II
Ideogram of chromosome II

Chocolate Memories

I appreciate the guest post, Emerson Moses

While watching direct TV trabuco cyn I came across a show on the Food Network where they were creating decadent sweets. It triggered a memory buried somewhere deep in my brain of a fudge recipe my mother used to make when I was a child. I picked up the phone and gave her a call to see if she too remembered the sweet confection she would stir up for me as a kid. Not only did she remember, but after a few minutes of scratching around, was able to locate the recipe. I grabbed a pen and pad and wrote it down. I was astonished how easy it was and to my surprise I had each and every ingredient needed to make it. Within minutes I had a bubbly pot of goodness waiting to be poured into a pan and chilled. When I gave some to my children after dinner, I knew the by the looks on their faces, this was going to be one of their favorites too.

Wednesday, December 28, 2011

Chromosome I

I have decided that I am going to debut a new "series" in which I go over each of the human chromosomes and information pertaining to it. Of course, I'm going to start off with Chromosome #1.

What is Chromosome I?
Chromosome 1 is the largest human chromosome, spanning about 247 million DNA building blocks (base pairs) and representing approximately 8 percent of the total DNA in cells. Chromosome 1 likely contains more than 3,000 genes, which perform a variety of different roles in the body.

How Do Changes in Chromosome I Affect Health?
The following chromosomal conditions are associated with changes in chromosome I (Not a complete list):

  • 1p36 deletion syndrome 
    • 1p36 deletion syndrome is caused by a deletion of genetic material from a specific region in the short (p) arm of chromosome 1. The signs and symptoms of this disorder, which include intellectual disability, distinctive facial features, and structural abnormalities in several body systems, are probably related to the loss of multiple genes in this region. The size of the deletion varies among affected individuals 
  • Neuroblastoma 
    • Neuroblastoma is a type of cancerous tumor composed of immature nerve cells (neuroblasts). These deletions are somatic mutations, which means they occur during a person's lifetime and are present only in the cells that become cancerous. About 25 percent of people with neuroblastoma have a deletion of 1p36.1-1p36.3, which is associated with a more severe form of neuroblastoma. Researchers believe the deleted region could contain a gene that keeps cells from growing and dividing too quickly or in an uncontrolled way, called a tumor suppressor gene. When tumor suppressor genes are deleted, cancer can occur. Researchers have identified several possible tumor suppressor genes in the deleted region of chromosome 1, and more research is needed to understand what role these genes play in neuroblastoma development. 
  • Thrombocytopenia-absent radius syndrome 
    • Everyone diagnosed with thrombocytopenia-absent radius (TAR) syndrome, which is characterized by bleeding problems and abnormal development of the forearms, has had a deletion of genetic material on chromosome 1. The deletion removes about 200,000 DNA building blocks (200 kilobases, or 200 kb) from the long (q) arm of the chromosome at position 1q21.1. This section of the chromosome contains 11 genes. The loss of multiple genes in this region is believed to be responsible for TAR syndrome. Not all people who inherit the deletion of genetic material on chromosome 1 associated with TAR syndrome will develop the disorder. Even within a single family, some people with the deletion may have TAR syndrome while others are unaffected. For this reason, researchers believe that the 1q21.1 200 kb deletion is needed to cause TAR syndrome but that some other, unknown genetic change must also be present. 
Diagramming Chromosome I
Below is an ideogram of Chromosome I, which shows its relative size and banding pattern. The banding pattern is the pattern of dark and light areas on the chromosome that are used to identify the location of genes on each chromosome.

Monday, December 19, 2011

Team Discovers Cause Of Rare Disease Childhood Disorder Called PKD Linked To Genetic Mutations

A large, international team of researchers led by scientists at the University of California, San Francisco has identified the gene that causes a rare childhood neurological disorder called PKD/IC, or "paroxysmal kinesigenic dyskinesia with infantile convulsions," a cause of epilepsy in babies and movement disorders in older children.

The study involved clinics in cities as far flung as Tokyo, New York, London and Istanbul and may improve the ability of doctors to diagnose PKD/IC, and it may shed light on other movement disorders, likeParkinson's disease.

The culprit behind the disease turns out to be a mysterious gene found in the brain called PRRT2. Nobody knows what this gene does, and it bears little resemblance to anything else in the human genome.

"This is both exciting and a little bit scary," said Louis Ptacek, MD, who led the research. Ptacek is the John C. Coleman Distinguished Professor of Neurology at UCSF and a Howard Hughes Medical Institute Investigator.

Discovering the gene that causes PKD/IC will help researchers understand how the disease works. It gives doctors a potential new way of definitively diagnosing the disease by looking for genetic mutations in the gene. The work may also shed light on other conditions that are characterized by movement disorders, including possibly Parkinson's disease.

"Understanding the underlying biology of this disease is absolutely going to help us understand movement disorders in general," Ptacek said.

About the Disease

PKD/IC strikes infants with epileptic seizures that generally disappear within a year or two. However, the disease often reemerges later in childhood as a movement disorder in which children suffer sudden, startling, involuntary jerks when they start to move. Even thinking about moving is enough to cause some of these children to jerk involuntarily.

The disease is rare, and Ptacek estimates strikes about one out of every 100,000 people in the United States. At the same time, the disease is classified as "idiopathic" which is just another way of saying we don't really understand it, Ptacek said.

If you take an image of the brain by MRI, patients with the disease all look completely normal. There are no injuries, tumors or other obvious signs that account for the movements as is often the case with movement disorders. Work with patients in the clinic had suggested a genetic cause, however.

"Sometimes we trace the family tree, and lo and behold, there is a history of it," said Ptacek. In the last several years, he and his colleagues have developed a large cohort of patients whose families have a history of the disease.

The new research was based on a cohort of 103 such families that included one or more members with the disease. Genetic testing of these families led to the researchers to mutations in the PRRT2 gene, which cause the proteins the gene encodes to shorten or disappear entirely in the brain and spinal cord, where they normally reside.

One possible explanation for the resulting neurological symptoms, the researchers found, relates to a loss of neuronal regulation. When the genetic mutations cause the gene products to go missing, the nerve cells where they normally appear may become overly excited, firing too frequently or strongly and leading to the involuntary movements. 
University of California, San Francisco. (2011, December 19). "Team Discovers Cause Of Rare Disease Childhood Disorder Called PKD Linked To Genetic Mutations." Medical News Today. Retrieved from

Mom and Me

Contributed by Alva Bender
Mom and I had been fighting a lot over the last few months so I suggested we go to counseling. I know that sounds crazy but since I live with my parentsI figured it was smarter to try and fix our relationship for the long haul rather than spend years and years going over the same exact issues time and again. It was actually a really good decision because she and I are better than we’ve ever been and we’re communicating on a whole new level. She sent me to the other day and had me pick out a satellite package without micromanaging me and I asked her to meet my boyfriend for the first time in my life. I feel like we’re both more excited about being around each other than we’ve been in years but you know, we’ve got a long way to go to become best friends. But maybe that’s just not the type of relationship we were meant to have at the end of the day!

Wednesday, November 2, 2011

Garrod's Fourth Inborn Error Of Metabolism: Modern Genetics Answers Age-Old Question

Garrod's Fourth Inborn Error Of Metabolism: Modern Genetics Answers Age-Old Question
Quite an interesting article, I would definitely suggest you read this if you have any interest in inborn errors of metabolism, this article primarily focuses on pentosuria, which is an inherited condition that is often mistaken for diabetes.

Saturday, October 22, 2011

A homemade kids vampire costume for the record books

Guest post written by Sarah Jones

I've always loved sewing and don't hesitate to break out my sewing machine whenever my kids need a costume or something mended. I think that they know that and especially appreciate it when Halloween rolls around every year. This year my son told me that he wanted to dress up as a vampire, but as a kid vampire. He told me that he wanted his outfit to be really cool, so I started thinking about it a few weeks ago and have started working on it.

He really loves space and rocket ships, so I thought that it would be cool to make him a cape with a lining of fabric with space ships all over it. I used my Clear Wireless Internet 4G to find a good pattern for a cape and set to work on it.

When I told him my idea for it, he was so impressed! So far the homemade kids vampire costume is looking so cute, but cool to an 8-year-old boy. I just have to get him some fangs and he'll be set!